SCHOTT TopPac® prefillable syringes (PFS)
Drug shelf life depends on material purity, inertness, and barrier properties of the storage container. Our basic material for SCHOTT TopPac® syringes, Cyclic Olefin Copolymer (COC ) – TO PAS® 6013 – is an advanced polymer which is manufactured in accordance with EP, JP, and USP class VI (DMF 12132). It is based on metallocene technology and used as the standard raw material for all available TopPac syringe formats.
The benefits of TOPAS® are:
- Transparent (glass-like appearance)
- No ion or heavy metal release due to biologically inert COC material
- Non-polar syringe contact surface
- Excellent moisture barrier properties
TopPac syringes offer optimal barrier properties for water vapor and oxygen permeability as well as light protection for the long-term storage of a broad range of parenteral products such as protein-based drugs or products with extreme pH values.
SCHOTT TopPac® prefillable syringes (PFS) are delivered in nest and tub configuration and are ready for filling process. Terminal sterilization (autoclaving) after filling is possible. SCHOTT TopPac® syringes are suitable for long-term storage as well as the administration of injectable drugs for a variety of therapeutic areas within the hospital care environment, clinical setting, or home care such as highly viscous drugs like hyaluronic acid, infusion therapy, biotech, or emergency drugs.
From small (1–5 ml) to large volume (10, 20, and 50 ml) syringes: Our injection molding process in combination with our COC raw material provides design flexibility to create customized solutions for specific drug applications.
